What is the Difference Between Botox, Dysport, and Jeuveau?


I’m Jinli Wu, a plastic surgery physician assistant in Beverly Hills and I would like to talk about a popular topic that my patients regularly ask me about: what is the difference between Botox, Dysport, and Jeuveau, and how do you know if you’re picking the right one for you?

First, let’s take a look at the science behind these products. Dysport, Botox, and Jeuveau are neuromodulators made from Botulimum toxin type A, a toxin derived from a bacteria called Clostridium botulinum. This is the same bacteria that causes botulism(!), though in small, controlled doses is very safe and effective at reducing fine lines and wrinkles.

Neuromodulars work at the molecular level by blocking the signal from your nerves to your muscles. When injected, it stops the nerves from releasing acetylcholine at the neuromuscular junction. This prevents the muscle from contracting, ultimately relaxing it. For example, when injected into key spots in the forehead, the muscles that aid in facial expression become paralyzed and those pesky horizontal lines are minimized. 

Dysport, Jeuveu, and Botox are all FDA approved to soften fine lines and dynamic wrinkles (wrinkles associated with facial movement) in the forehead and in between and around the eyes, like crow’s feet. They are also used to treat chin dimples, reduce neck lines, elevate eyebrows, and slim the jawline. The side effects for Dysport and Jeuveau are the same as Botox, which include injection site discomfort and bruising.

So what are the differences between Botox, Dysport, and Jeuveau?

Botox has been on the market for over 30 years and has a great safety and efficacy profile. It takes approximately 4-7 days to take effect and up to 2 weeks for full results. Dysport has also been used for many years in both Europe and the USA with great results. Clinical studies show that Dysport may last up to 4 months, similar to Botox; however, some patients find that Dysport may act quicker and last longer. Still, some people find there is no difference between the two. The effects of Dysport can be seen in 2-3 days with maximum results achieved in 2 weeks. 

A key advantage of Dysport is that it can create a more natural appearance for those patients who prefer some muscle movement or want quicker results. For those who have stopped responding to Botox, it may also be a useful alternative. Dysport is also unique in that it requires more units to achieve the same results as Botox, however, because it costs less per unit, the cost per treatment is equivalent in our clinic.

Jeuveau is a newer generation of neuromodulators and is FDA-approved to treat frown-lines between the eyebrows, though it can be used in the same areas as Dysport and Botox. Studies comparing the efficacy of Jeuveau to Botox show that Jeuveau works just as well. Jeuveau’s characteristics are very similar to Botox, even down to the size of the molecule’s themselves. Compared to Dysport, which is smaller, Botox and Jeuveau do not diffuse as much, which means it is less likely to move to nearby muscles.  Similar to Botox, Jeuveau takes about 4-7 days to take effect and up to 2 weeks for maximum results.

Most patients come in to the office asking for Botox because it is the most recognizable brand. When it comes to choosing a neuromodulator for you, there isn’t one right answer. Basically, it comes down to each drug’s individual profile, the needs of the patient, and the technique of the injector. These details, and your aesthetic goals will help guide the best treatment plan for you.

I hope this post clarifies some of the key differences between these neuromodulators, which are used frequently in our clinic. If you have any questions, or know of any other topic you would like me to discuss, please let me know!

Have a great day and I look forward to seeing you in clinic!


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About Jinli Wu

Jinli Wu is a Plastic Surgery Physician Assistant in Beverly Hills, CA.
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