Category Archives: salmon dna

Polydeoxyribonucleotide (PDRN) / Polynucleotide (PN) and Rejuran® — current evidence and clinical perspective

Posted on September 24, 2025 by Donald B. Yoo, M.D.

Summary: Polydeoxyribonucleotide (PDRN) and related polynucleotide (PN) preparations — including the commercial product Rejuran® (salmon-derived PN/PDRN formulations) — are DNA-derived biopolymers investigated for tissue regeneration, wound healing, and aesthetic rejuvenation. Preclinical data support mechanisms via adenosine A₂A receptor activation, angiogenesis, … Continue reading →

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